Human lupus-type inclusions in umbilical cord blood mononuclear cells
نویسندگان
چکیده
منابع مشابه
Therapeutic Benefit of Intravenous Administration of Human Umbilical Cord Blood- Mononuclear Cells Following Intracerebral Hemorrhage in Rat
Objective(s) Human umbilical cord blood (HUCB) is now considered as a valuable source for stem cell–based therapies. Previous studies showed that intravascular injection of the HUCB significantly improves neurological functional recovery in a rat model of intracerebral hemorrhage (ICH). In the present study, we hypothesize transplanted HUCB derived mononuclear cells (UC-MCs) can decrease injur...
متن کاملIsolation and Characterization of Mesenchymal Stem Cells Derived from Human Umbilical Cord Blood Mononuclear Cells
and Laboratory of Regenerative Medicine, Department of Medical Research, and Department of Surgery, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan. Received: June 24, 2015 Accepted: March 16, 2016 Address reprint request and correspondence to: Ying-Hsien Kao, Laboratory of Regenerative Medicine, Department of Medical Research, and Po-Huang Lee, Department of Surgery, E-Da Hospital, No. 1, ...
متن کاملGeneration of Induced Pluripotent Stem Cells with High Efficiency from Human Umbilical Cord Blood Mononuclear Cells
Human induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine. Generating iPSCs from immunologically immature newborn umbilical cord blood mononuclear cells (UCBMCs) is of great significance. Here we report generation of human iPSCs with great efficiency from UCBMCs using a dox-inducible lentiviral system carrying four Yamanaka factors. We generated these cells by op...
متن کاملIntra-arterial transplantation of human umbilical cord blood mononuclear cells in neonatal hypoxic-ischemic rats.
UNLABELLED Based on preclinical findings, cellular therapy has become a promising therapeutic approach for neonatal hypoxia-ischemia (HI). However, before translation into the clinical setting, new and effective routes of cell delivery must be determined. Intra-arterial (IA) delivery is an attractive route of cellular administration but has never been used in neonatal HI rats. AIMS In this st...
متن کاملHypoxia Preconditioning Promotes Survival And Clonogenic Capacity Of Human Umbilical Cord Blood Mesenchymal Stem Cells
Background: In recent decade, human umbilical cord blood derived mesenchymal stem cells (hUCB-MSCs) provide enormous potential for appropriate cell therapy, but they have limited growth potential and cease to proliferate due to cellular senescence, so providing a strategy for increasing the stem cell survival is necessary. Methods: In this investigation, MSCs characterized by flow cytome...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1990
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780330915